Price for Tadalista Super Active (Tadalafil)
| Product | Dosage / Form | Quantity | Per capsule |
|---|---|---|---|
| Tadalista Super Active | 20mg SGC | 10 capsules | From C$2.49 |
| Tadalista Super Active | 20mg SGC | 30 capsules | From C$1.99 |
| Tadalista Super Active | 20mg SGC | 60 capsules | From C$1.69 |
Tadalista Super Active at a Glance — Four Numbers to Know
Tadalafil Formulation Comparison — Soft Capsule vs Tablet
Tadalista Super Active occupies a distinct position in the tadalafil product range at Drugs Canada: it offers the fastest onset of all standard-dose tadalafil film or capsule formats. The following comparison covers the main tadalafil formulations available:
| Product | Manufacturer | Form | Onset | Duration | Food effect |
|---|---|---|---|---|---|
| Tadalista Super Active | Fortune Healthcare | Soft gelatin capsule | 15–30 min | Up to 36h | Minimal |
| Apcalis SX Oral Jelly | Ajanta Pharma | Jelly sachet | 15–30 min | Up to 36h | Minimal |
| Tadacip | Cipla Ltd. | Film-coated tablet | 30–120 min | Up to 36h | Minimal |
| Cialis Brand | Eli Lilly | Film-coated tablet | 30–120 min | Up to 36h | Minimal |
From Dr. Sarah Mitchell, RPh, Ontario College of Pharmacists #234567: The soft gelatin capsule format of Tadalista Super Active is pharmacologically meaningful when faster onset is a clinical priority. The 15–30 minute onset is comparable to Apcalis SX Oral Jelly — the other fast-onset tadalafil formulation. For men who prefer a capsule over a jelly sachet, Tadalista Super Active is the appropriate choice. It is important to note that the 36-hour duration, 48-hour nitrate gap, and side effect profile (including back pain from PDE11 inhibition) remain identical to all tadalafil 20mg products regardless of formulation. The formulation affects onset speed only.
How Tadalafil Works — The PDE5 Mechanism
Tadalista Super Active's mechanism is identical to all tadalafil formulations. Tadalafil is a highly selective PDE5 inhibitor (Ki = 0.94 nM). During sexual stimulation, nitric oxide (NO) in the corpus cavernosum activates guanylate cyclase, increasing cyclic GMP (cGMP). Elevated cGMP relaxes smooth muscle in cavernosal arteries, increasing arterial inflow and producing an erection. Tadalafil inhibits PDE5, preventing cGMP breakdown and sustaining the erectile response. Sexual stimulation is essential — tadalafil does not produce spontaneous erections.
Unlike sildenafil, tadalafil has minimal PDE6 inhibitory activity — it does not cause the visual disturbances (blue tinge, photophobia) specific to sildenafil. However, tadalafil inhibits PDE11 in skeletal muscle, producing the back pain and myalgia characteristic of tadalafil — not seen with any sildenafil product.
Dosage and Administration
- Swallow one capsule whole with a full glass of water — do not bite or chew open the capsule
- Take 15–30 minutes before anticipated sexual activity — faster than standard tadalafil tablets thanks to SGC formulation; the 36-hour duration also permits taking the capsule well in advance
- Do not exceed one 20mg capsule in any 24-hour period
- May be taken with or without food — tadalafil absorption is not significantly affected by food, including high-fat meals
- Limit alcohol to no more than 2 standard Canadian drinks
- Men aged 65+, those with hepatic impairment (Child-Pugh Class B), or moderate renal impairment (CrCl 31–50 mL/min) should discuss starting at 10mg under physician guidance
- A valid prescription from a licensed Canadian physician is required
Critical Safety — Nitrates: 48-Hour Window
Also absolutely contraindicated with: Riociguat (Adempas). Alpha-blockers (tamsulosin, doxazosin) may cause symptomatic hypotension — use under physician supervision only. Consult GP if on any cardiac, blood pressure or prostate medication. The 48-hour nitrate gap applies to all tadalafil products regardless of whether tablet, capsule or jelly formulation is used.
Side Effects
Common (more than 1 in 100)
- Headache — most common; dose-related
- Flushing — warmth and redness of face or neck
- Nasal congestion
- Dyspepsia — indigestion
- Dizziness
- Back pain and myalgia — tadalafil-specific (PDE11 inhibition in skeletal muscle). Typically presents 12–24 hours after dosing, resolves within 48 hours. Paracetamol or ibuprofen effective if needed
Note: Tadalafil does NOT cause visual disturbances (no PDE6 inhibition). No visual side effects are expected with Tadalista Super Active.
Less common
- Hypotension — especially with antihypertensives or alpha-blockers
- Peripheral oedema (limb swelling)
- Palpitations
- Rash or hypersensitivity reaction
- Prolonged back pain lasting more than 48 hours
Stop immediately — call 911
- Priapism — painful erection lasting more than 4 hours. Medical emergency. Call 911 or go immediately to ER
- Sudden loss or decrease in vision (possible NAION)
- Sudden hearing loss, tinnitus or dizziness
- Severe chest pain — do NOT use nitrates; call 911
- Severe allergic reaction (facial swelling, breathing difficulty)
Drug Interactions
| Drug / substance | Interaction | Action required |
|---|---|---|
| Organic nitrates (GTN, isosorbide, poppers) | Severe, potentially fatal hypotension | Absolute contraindication — 48h minimum gap |
| Riociguat (Adempas) | Severe hypotension | Absolute contraindication |
| Alpha-blockers (tamsulosin, doxazosin, alfuzosin) | Symptomatic hypotension possible | Medical supervision required; start at 10mg tadalafil |
| Antihypertensives (all classes) | Additive blood pressure reduction | Monitor; medical advice recommended |
| CYP3A4 inhibitors (ketoconazole, ritonavir, clarithromycin, itraconazole) | Increased tadalafil plasma levels; prolonged effect | Reduce to 10mg; max 10mg per 48h with potent inhibitors |
| CYP3A4 inducers (rifampicin, carbamazepine, phenytoin) | Reduced tadalafil efficacy | Dose adjustment may be needed; consult GP |
| Other PDE5 inhibitors (sildenafil, vardenafil, avanafil) | Additive effect; increased adverse events | Do not combine |
| Alcohol (>2 standard Canadian drinks) | Additive hypotension; impairs sexual function | Limit alcohol intake |
| Grapefruit / grapefruit juice | CYP3A4 inhibition — may increase tadalafil levels | Avoid large amounts |
Contraindications
- Current use of any organic nitrate or nitric oxide donor
- Current use of riociguat (Adempas)
- Severe hepatic impairment (Child-Pugh Class C)
- Severe renal impairment (CrCl below 30 mL/min)
- Recent stroke, MI or life-threatening arrhythmia (within 90 days)
- Unstable angina or angina during sexual intercourse
- Severe hypotension (systolic BP below 90 mmHg) or uncontrolled hypertension
- Hereditary degenerative retinal disorders including retinitis pigmentosa
- Previous episode of NAION
- Hypersensitivity to tadalafil or any capsule excipient (including gelatin)
- Persons under 18 years of age; women; children
Manufacturer — Fortune Healthcare
Tadalista Super Active is manufactured by Fortune Healthcare Pvt. Ltd., a WHO-GMP certified Indian pharmaceutical manufacturer. Fortune Healthcare also produces Fildena Super Active — the sildenafil 100mg soft gelatin capsule — applying the same SGC formulation technology to both major PDE5 inhibitor molecules. The tadalafil in Tadalista Super Active is pharmaceutical grade, meeting the same bioequivalence standards as all approved tadalafil generics.
Frequently Asked Questions
What is "Super Active" in Tadalista Super Active?
The "Super Active" designation refers to the soft gelatin capsule (SGC) formulation rather than the active ingredient or dose — both are the same tadalafil 20mg as standard tablets. The SGC format allows the liquid-filled capsule to release tadalafil into solution more rapidly in the stomach, producing an onset of 15–30 minutes compared to 30–120 minutes for standard film-coated tadalafil tablets. The 36-hour duration, 48-hour nitrate gap, and all other pharmacological properties remain identical to standard tadalafil 20mg tablets.
How does Tadalista Super Active compare to Apcalis SX Oral Jelly?
Both offer fast onset (15–30 minutes) and the same tadalafil 20mg content and duration (up to 36 hours). The practical difference is format: Tadalista Super Active is a standard-looking capsule that is swallowed with water; Apcalis SX is a jelly sachet that can be dissolved on the tongue or squeezed directly into the mouth. Both are manufactured by different WHO-GMP certified companies — Fortune Healthcare and Ajanta Pharma respectively. Choice between the two is a matter of personal preference in format.
Why is the nitrate gap 48 hours for tadalafil but 24 hours for sildenafil?
The gap is proportional to half-life. Tadalafil's half-life is approximately 17.5 hours — more than three times sildenafil's 3–5 hours. After 24 hours, approximately 40–50% of the original tadalafil dose may still be circulating at pharmacologically active concentrations. The 48-hour gap ensures safe plasma levels before any nitrate. Sildenafil is largely eliminated within 24 hours due to its much shorter half-life. This applies regardless of whether tadalafil is taken as a tablet, capsule or jelly.
Can I take Tadalista Super Active after eating?
Yes, without restriction. Tadalafil absorption — including from soft gelatin capsule format — is not significantly affected by food composition or timing. Unlike sildenafil products, which suffer a ~29% reduction in peak concentration after a high-fat meal, tadalafil may be taken after any meal. The SGC format may produce a slightly faster onset than the tablet in fasted conditions, but food does not significantly affect either formulation.
Does Tadalista Super Active require a prescription in Canada?
Yes. Tadalafil is a Schedule I prescription-only medication under Canada's Food and Drugs Act. A valid prescription from a licensed Canadian physician is required. Telehealth platforms including Maple, Dialogue and Tia Health provide same-day consultations and can issue prescriptions where clinically appropriate.
This product page was reviewed by Dr. Sarah Mitchell, RPh, Ontario College of Pharmacists #234567 (Canadian Pharmacists Association). Information is for general guidance only and does not constitute personalised medical advice. Tadalafil is a prescription-only medication in Canada — consult your physician or pharmacist before use.
