Medically reviewed by Dr. Sarah Mitchell, RPh, Clinical Pharmacist — Updated March 2026
Critical Clarification — Lovegra (Sildenafil) vs Addyi (Flibanserin) vs Viagra
Female sexual dysfunction is not a single condition — and the medications used to treat it work through completely different mechanisms. Before purchasing any treatment, Canadian women need to understand the distinction between these three products.
| Lovegra (Sildenafil Citrate) | Addyi (Flibanserin) | Viagra / Sildenafil (for men) | |
|---|---|---|---|
| Active ingredient | Sildenafil Citrate 100 mg | Flibanserin 100 mg | Sildenafil Citrate 25–100 mg |
| Mechanism | PDE5 inhibitor — increases genital blood flow | Serotonin/dopamine modulator — acts on brain neurotransmitters | PDE5 inhibitor — increases penile blood flow |
| Treats | Female Sexual Arousal Disorder (FSAD) — physical response | Hypoactive Sexual Desire Disorder (HSDD) — low libido | Erectile dysfunction |
| Works on | Body — genital vasodilation | Brain — desire and libido | Body — penile vasodilation |
| Onset of action | 30–60 minutes | Weeks to months of daily use | 30–60 minutes |
| How it is taken | On demand — before sexual activity | Daily — at bedtime | On demand — before sexual activity |
| Health Canada approval | Not approved for women — off-label / grey area import | Not approved in Canada (approved in USA only) | Approved for men |
| Best suited for | Women who want improved physical arousal (lubrication, sensation) during sex | Premenopausal women with consistently low sexual desire | Men with erectile dysfunction |
The bottom line for Canadian women: If your primary issue is low sexual desire — you want to want sex but don't — Addyi (Flibanserin) targets the brain pathways associated with libido. If your issue is physical arousal during sex — difficulty with sensation, lubrication, or genital response despite desire — Lovegra (Sildenafil) addresses the physical vascular response. Many women experience both, which is why discussion with a healthcare provider is strongly recommended before starting either medication.
How Does Lovegra Work in Women?
Sildenafil Citrate is a PDE5 inhibitor (phosphodiesterase type 5 inhibitor). During sexual arousal, nitric oxide (NO) is released in genital tissue, stimulating production of cGMP (cyclic guanosine monophosphate). cGMP relaxes smooth muscle in blood vessels of the clitoris and vaginal walls, allowing increased blood flow — producing clitoral engorgement, enhanced sensitivity, and increased vaginal lubrication.
PDE5 is the enzyme that breaks down cGMP. Sildenafil inhibits PDE5, preserving elevated cGMP levels and sustaining the physiological arousal response during sexual stimulation.
Female anatomy and Sildenafil: The clitoris contains erectile tissue structurally homologous to the male corpus cavernosum — the same tissue that Sildenafil acts upon in men. Female genital arousal involves the same nitric oxide/cGMP pathway as male erection. This is why Sildenafil produces measurable physiological effects in women as well as men.
Critical: Lovegra works only with sexual stimulation. Without arousal, no physiological response occurs — it is not an aphrodisiac and does not increase sexual desire or libido. It addresses physical arousal response, not desire.
Who Is Lovegra Appropriate For?
Sildenafil has been studied in several specific populations of women where physical arousal response is impaired. The most clinically meaningful evidence exists for:
SSRI-induced sexual dysfunction: Antidepressants (SSRIs and SNRIs — fluoxetine/Prozac, sertraline/Zoloft, escitalopram/Cipralex, venlafaxine/Effexor) are among the most common causes of female sexual dysfunction in Canadian women, affecting an estimated 30–70% of female SSRI users. SSRI-induced sexual dysfunction predominantly affects arousal and orgasm — exactly the physiological response that Sildenafil addresses. Multiple clinical studies have shown Sildenafil to be effective for SSRI-induced arousal disorder, making this one of the strongest evidence-based applications for Lovegra in Canadian women.
Menopausal and postmenopausal women: Oestrogen decline during menopause reduces genital blood flow, vaginal lubrication, and clitoral sensitivity. Sildenafil's vasodilatory mechanism can partially compensate for this reduced vascular response independently of oestrogen levels. Canadian women in perimenopause or postmenopause who experience diminished physical arousal despite normal desire may find Lovegra beneficial — either alone or as a complement to hormone replacement therapy (HRT).
Diabetic women with sexual dysfunction: Diabetes affects vascular function systemically — including genital vasculature. Women with type 1 or type 2 diabetes have higher rates of female sexual dysfunction than the general population. The PDE5 pathway is intact in most diabetic women, making Sildenafil potentially effective even when vascular function is otherwise impaired.
Women with spinal cord injury: Studies have demonstrated Sildenafil to improve genital arousal response in women with spinal cord injuries — a population with significant unmet sexual health needs.
Lovegra is less likely to be appropriate for women whose primary complaint is low desire or low libido without a physical arousal component. For primary desire disorder (HSDD), psychological, hormonal, or other approaches are more appropriate — and Addyi (Flibanserin), while not approved in Canada, is the pharmacological option targeting this specific condition.
Dosage Guide — Lovegra for Canadian Women
Standard dose: 50 mg (half a 100 mg Lovegra tablet, split with a pill cutter) is the recommended starting dose for most women. Take approximately 30 to 60 minutes before planned sexual activity.
Dose options:
- 25 mg — for women over 65, those with hepatic impairment, or women taking medications that may increase Sildenafil blood levels (certain antifungals, some antibiotics, HIV medications)
- 50 mg — standard starting dose for most women
- 100 mg — full tablet. Use only if 50 mg is insufficient after multiple attempts. Do not exceed 100 mg in 24 hours
With or without food: For fastest and most reliable onset, take on an empty stomach or at least 2 hours after a meal. High-fat meals significantly delay Sildenafil absorption and reduce peak concentration — the most common reason Lovegra appears to work inconsistently.
Frequency: No more than once per 24 hours. Lovegra is an on-demand medication — it is not taken daily.
First-time use: Allow at least 4 to 6 attempts before concluding whether Lovegra is effective. The physiological response may take several occasions to optimise, and any degree of anxiety on first use can blunt the effect.
Is Lovegra Legal in Canada? — Health Canada and Legal Status
Health Canada status: Sildenafil Citrate is approved by Health Canada as a prescription medication for erectile dysfunction in men. It is not specifically approved by Health Canada for female sexual dysfunction. Lovegra (Sildenafil by Ajanta Pharma) is not individually registered with Health Canada under the Lovegra brand name and does not have a Canadian Drug Identification Number (DIN).
Off-label prescribing in Canada: Canadian doctors may legally prescribe Sildenafil off-label for female sexual dysfunction at their clinical discretion — this is consistent with standard Canadian medical practice. Some Canadian gynaecologists and sexual health specialists do prescribe Sildenafil to women, particularly for SSRI-induced sexual dysfunction.
Buying Lovegra from international online pharmacies: Purchasing Sildenafil from international online pharmacies for personal use in small quantities exists in a legal grey area in Canada. The Canada Border Services Agency (CBSA) may intercept shipments of prescription medications from non-approved sources. For personal-use quantities from reputable sources, enforcement against individual consumers is rare — but not impossible.
Our recommendation: Discuss female sexual dysfunction with a Canadian gynaecologist, family physician, or sexual health specialist before starting Lovegra. Telehealth platforms including Maple, Dialogue, and Tia Health offer convenient same-day consultations for women's sexual health across Canada.
Price Comparison — Lovegra in Canada
| Private prescription Sildenafil (Canadian pharmacy) | Lovegra (drugs-canada.com) | |
|---|---|---|
| 100 mg per pill | CAD$15–25 per pill | From $1.92 USD per pill |
| Format | Generic Sildenafil tablet | Lovegra tablet — Ajanta Pharma GMP-certified |
| Prescription required | Yes — from Canadian doctor | Grey area — Personal importation |
| Delivery | Same day at pharmacy | 4–9 business days to all Canadian provinces |
Drug Interactions — What Canadian Women Must Know
Lovegra contains Sildenafil Citrate — the same interactions that apply to Viagra in men apply equally to Lovegra in women. Always inform your doctor or pharmacist about all medications you take before using Lovegra.
Absolute contraindications — never combine:
- Nitrate medications (nitroglycerin/GTN spray, isosorbide dinitrate, isosorbide mononitrate) — used for heart conditions. The combination causes severe, potentially life-threatening hypotension. This applies equally to women and men. Absolute contraindication — no safe dose of Lovegra for women taking nitrates.
- Poppers (amyl nitrite, butyl nitrite) — same dangerous blood pressure drop as cardiac nitrates.
- Riociguat (Adempas) — used for pulmonary hypertension. Severe hypotension. Absolute contraindication.
- Other PDE5 inhibitors — never combine two medications from the same class.
Clinically important interactions for women specifically:
- SSRIs and SNRIs (fluoxetine, sertraline, escitalopram, paroxetine, venlafaxine, duloxetine): Some SSRIs — particularly fluoxetine and fluvoxamine — are CYP2C9 inhibitors that can modestly increase Sildenafil blood levels. This is generally not clinically significant at standard doses but worth noting. Sildenafil is frequently used specifically to counteract SSRI-induced sexual dysfunction — the combination at appropriate doses is generally safe.
- Strong CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir, clarithromycin, erythromycin) — significantly increase Sildenafil levels. Start at 25 mg maximum when taking these medications.
- Alpha-blockers (sometimes prescribed to women for certain conditions) — additive blood pressure lowering effect. Caution and medical supervision required.
- Hormonal contraceptives: No clinically significant pharmacokinetic interaction with combined oral contraceptives.
- Alcohol — one to two standard Canadian drinks are tolerable for most healthy women. Larger amounts increase dizziness and blood pressure lowering effects and should be avoided.
- Grapefruit juice — can increase Sildenafil blood levels. Best avoided on the day of use.
Side Effects of Lovegra (Sildenafil) in Women
The side effect profile of Sildenafil in women is similar to that in men:
Common side effects (affect 1 in 10 users):
- Headaches
- Facial flushing
- Nasal congestion
- Indigestion or upset stomach
- Dizziness
- Visual disturbances — blue tinge, increased light sensitivity (due to PDE6 cross-reactivity)
Rare but serious — seek immediate medical attention:
- Severe allergic reactions (swelling of face, lips, throat — difficulty breathing)
- Sudden vision loss — stop immediately and seek urgent medical care
- Sudden hearing loss
- Significant blood pressure drop — particularly if taking cardiovascular medications
- Chest pain during or after sexual activity — stop immediately and call 911
Who Should Not Take Lovegra
Lovegra (Sildenafil) is contraindicated in women who:
- Take nitrate medications or nitric oxide donors in any form
- Take riociguat (Adempas)
- Have severe cardiovascular disease or recent heart attack or stroke (within 6 months)
- Have severe hepatic impairment
- Have hereditary degenerative retinal disorders (retinitis pigmentosa)
- Have uncontrolled hypotension (blood pressure below 90/50 mmHg)
- Have a history of non-arteritic anterior ischaemic optic neuropathy (NAION)
- Are pregnant — Sildenafil should only be used in pregnancy under specialist supervision for pulmonary hypertension, not for sexual dysfunction
- Are breastfeeding — safety data insufficient
- Are under 18 years of age
Delivery to All Canadian Provinces
drugs-canada.com ships discreetly to all Canadian provinces and territories. Standard delivery: 4–9 business days.
Ontario (Toronto, Ottawa, Mississauga, Hamilton, Brampton) — British Columbia (Vancouver, Victoria, Surrey, Kelowna) — Quebec (Montreal, Quebec City, Laval, Gatineau) — Alberta (Calgary, Edmonton, Red Deer) — Manitoba (Winnipeg) — Saskatchewan (Saskatoon, Regina) — Nova Scotia (Halifax) — New Brunswick (Moncton, Fredericton) — and all remaining provinces and territories.
Frequently Asked Questions — Lovegra (Female Viagra) in Canada
Is Lovegra the same as Viagra? Lovegra contains the same active ingredient — Sildenafil Citrate 100 mg — as Viagra and works through the same PDE5 inhibition mechanism. The difference is that Lovegra is specifically marketed and packaged for women by Ajanta Pharma. The pharmacological action, onset (30–60 minutes), duration (4–6 hours), and side effects are identical to male Sildenafil.
Does Lovegra increase sexual desire? No. Lovegra (Sildenafil) addresses physical arousal — enhancing genital blood flow, clitoral engorgement, and vaginal lubrication during sexual activity. It does not increase sexual desire or libido. For low libido specifically, Addyi (Flibanserin) targets brain neurotransmitters — but is not approved in Canada.
What is the difference between Lovegra and Addyi? Completely different mechanisms and target conditions. Lovegra (Sildenafil) = PDE5 inhibitor = enhances physical genital response during sex when arousal is present. Addyi (Flibanserin) = serotonin/dopamine modulator = addresses low libido and desire. Lovegra is taken on-demand before sex; Addyi is taken daily at bedtime. Neither is Health Canada-approved for female sexual dysfunction.
Is female Viagra legal in Canada? Sildenafil is not approved by Health Canada for female sexual dysfunction. Canadian doctors can prescribe it off-label at their discretion. Purchasing from international online pharmacies for personal use in small quantities exists in a grey area — the CBSA may intercept shipments, though enforcement against personal-use quantities is rare.
How long does Lovegra take to work? 30 to 60 minutes after taking it, ideally on an empty stomach. Physical effects — increased genital blood flow, lubrication, and sensitivity — occur in response to sexual stimulation within this time window. High-fat meals can delay onset by 60 to 90 minutes.
Can women on antidepressants (SSRIs) take Lovegra? SSRI-induced sexual dysfunction is one of the most evidence-based applications for Sildenafil in women. The combination at appropriate doses is generally safe. Some SSRIs can modestly increase Sildenafil blood levels — starting at 25 to 50 mg is prudent for women on SSRIs. Always consult your prescribing doctor before combining.
Can menopausal women take Lovegra? Yes — menopausal and postmenopausal women are one of the populations where Sildenafil has shown the most consistent benefit for physical arousal. Oestrogen decline reduces genital blood flow; Sildenafil compensates through the nitric oxide/cGMP pathway independently of oestrogen levels. Lovegra and hormone replacement therapy (HRT) address complementary aspects of menopausal sexual dysfunction.
How long does Lovegra last? 4 to 6 hours — identical to the male formulation, as the active ingredient and dosage are the same. In some women the effect lasts up to 8 hours.
Can I take Lovegra with alcohol? One to two standard Canadian drinks are generally tolerable. Larger amounts should be avoided — alcohol lowers blood pressure and can independently impair sexual response.
How long does delivery to Canada take? Standard delivery to all Canadian provinces takes 4 to 9 business days. All orders are delivered in plain, unmarked packaging with no reference to the contents or sender. A tracking number is included with every order.




