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Serophene

Serophene
Serophene is an ovulatory stimulant that is used for treating female infertility.

Brand: Clomiphene

Availability: In Stock
Average Delivery Time: 9 Days
Exp. Date: June 2024
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Package Price Per pill Save Order
Serophene 100 mg
120 pills - 100 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$184.99 $1.54 $88.25 Add to cart
90 pills - 100 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$148.75 $1.65 $56.18 Add to cart
60 pills - 100 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$109.95 $1.83 $26.67 Add to cart
30 pills - 100 mg $68.31 $2.28 No Add to cart
Serophene 50 mg
360 pills - 50 mg
+ 8 free Viagra 100 mg, 5% discount for future orders
$289.19 $0.80 $197.41 Add to cart
180 pills - 50 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$149.93 $0.83 $93.37 Add to cart
120 pills - 50 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$101.91 $0.85 $60.29 Add to cart
90 pills - 50 mg $78.37 $0.87 $43.28 Add to cart
60 pills - 50 mg $59.93 $1.00 $21.17 Add to cart
30 pills - 50 mg $40.55 $1.35 No Add to cart
Serophene 25 mg
360 pills - 25 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$157.69 $0.44 $70.01 Add to cart
180 pills - 25 mg $84.67 $0.47 $29.18 Add to cart
120 pills - 25 mg $59.34 $0.49 $16.56 Add to cart
90 pills - 25 mg $45.91 $0.51 $11.02 Add to cart
60 pills - 25 mg $37.95 $0.63 No Add to cart

Product description

Drug Title

Serophene (Clomiphene)

Pharmacological action

Stimulator of gonadotropin production. A remedy with anti-estrogenic and estrogenic activity. It has a non-steroidal structure, which is close to chlorotrianisene. It is believed that the action of clomiphene is due to specific binding to estrogen receptors of the hypothalamus and pituitary gland, which increases the secretion of gonadotropic hormones of the pituitary gland. This in turn stimulates the maturation and endocrine activity of the follicle in the ovary, as well as the subsequent formation and stimulation of the corpus luteum function. In high doses it inhibits the secretion of gonadotropins. It does not have gestagenic and androgenic activity.


Pharmacokinetics

When taken orally it is well absorbed from the gastrointestinal tract. It is metabolized in the liver. It is subject to intestinal-hepatic recirculation. T1/2 is 5-7 days. It is mainly excreted with bile.

Contraindications to use

Hypersensitivity to clomiphene; hepatic and/or renal insufficiency; pregnancy, lactation (breast-feeding); ovarian cysts (except for polycystic ovary syndrome); tumor or hypothyroidism; Thyroid or adrenal dysfunction; metrorrhagia of unclear etiology; long-term or recently developed visual impairment; genital neoplasms; endometriosis; ovarian failure due to hyperprolactinemia.


Administration during pregnancy and lactation

Prohibited for use during pregnancy and lactation (breast-feeding).

Administration with liver dysfunction

Contraindicated use in liver failure.

Administration in patients with impaired renal function

Administration in renal failure is contraindicated.

Indications of the active substances of the drug Serophene (Clomiphene)

Anovulatory infertility (ovulation induction); amenorrhea (dysgonadotropic form), secondary amenorrhea, postcontraceptive amenorrhea; Stein-Leventhal syndrome (polycystic ovary syndrome); Oligomenorrhea; galactorrhea (against a pituitary tumor); Chiari-Frommel syndrome (prolonged postpartum amenorrhea-galactorrhea syndrome); androgen deficiency; in men - oligospermia.


Dosing regimen

The optimal dosing regimen is determined by the doctor. Should strictly follow the compliance of the dosage form used by a particular drug indications for use and the dosing regimen.

It is taken orally. The dose and regimen of administration is determined by the individual