Loading...



Shopping cart processing ...
0
Your cart0
Products 0
Price $0.00
Bestsellers Pill categories
Customer Support 24/7
usa canada USA
uk UK
au AU
Live Chat 24/7
Menu
Customer Support 24/7
USA/Canada Toll Free USA
UK UK
AUS AU
Customer Support 24/7
usacanada USA
uk UK
au AU
We accept
  • Visa
  • MasterCard
  • Amex
  • JCB
Currency
USD
Your cart: $0.00 (0 items)
Checkout

Categories list

Choosing us you get:

  • Reliable supplier
  • Low Internet prices
  • Free bonus pills
  • Discount on all future orders
  • Discreet package
  • SSL secure orders
Worldwide Shipping!

Testimonials:

  • Leo Ahlstrom Werribee, Australia
    I can hardly believe that I spent so much money on brand drugs. Your generic drugs act the same way the brand ones do but they cost much more cheaper. Thank you. Now I know about your site and will buy again and again.
More info »

Risperdal

Risperdal
Risperdal is an atypical antipsychotic that is used in the treatment of schizophrenia or bipolar mania. Doctors may also prescribe it for other conditions if found appropriate.

Brand: Risperidone

Availability: In Stock
Average Delivery Time: 9 Days
Exp. Date: May 2024
View product image
Package Price Per pill Save Order
Risperdal 4 mg
360 pills - 4 mg
+ 12 free Viagra 100 mg, 7% discount for future orders
$305.95 $0.85 $161.93 Add to cart
180 pills - 4 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$165.05 $0.92 $68.89 Add to cart
120 pills - 4 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$119.93 $1.00 $36.03 Add to cart
90 pills - 4 mg $95.93 $1.07 $21.04 Add to cart
60 pills - 4 mg $69.95 $1.17 $8.03 Add to cart
30 pills - 4 mg $38.99 $1.30 No Add to cart
Risperdal 3 mg
360 pills - 3 mg
+ 8 free Viagra 100 mg, 5% discount for future orders
$261.95 $0.73 $121.93 Add to cart
180 pills - 3 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$134.99 $0.75 $56.95 Add to cart
120 pills - 3 mg $95.99 $0.80 $31.97 Add to cart
90 pills - 3 mg $77.99 $0.87 $17.98 Add to cart
60 pills - 3 mg $57.99 $0.97 $5.99 Add to cart
30 pills - 3 mg $31.99 $1.07 No Add to cart
Risperdal 2 mg
360 pills - 2 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$186.99 $0.52 $88.89 Add to cart
180 pills - 2 mg $98.95 $0.55 $38.99 Add to cart
120 pills - 2 mg $71.97 $0.60 $19.99 Add to cart
90 pills - 2 mg $57.92 $0.64 $11.05 Add to cart
60 pills - 2 mg $40.91 $0.68 $5.07 Add to cart
30 pills - 2 mg $22.99 $0.77 No Add to cart
Risperdal 1 mg
360 pills - 1 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$153.99 $0.43 $61.41 Add to cart
180 pills - 1 mg $80.99 $0.45 $26.71 Add to cart
120 pills - 1 mg $57.93 $0.48 $13.87 Add to cart
90 pills - 1 mg $45.99 $0.51 $7.86 Add to cart
60 pills - 1 mg $31.99 $0.53 $3.91 Add to cart
30 pills - 1 mg $17.95 $0.60 No Add to cart

Product description

DRUG TITLE

Risperdal (Risperidone)

Pharmacological action

Antipsychotic agent (neuroleptic), benzizoxazole derivative. It has a high affinity for serotonin 5-HT2- and dopamine D2-receptors. It binds to α1-adrenoreceptors and, with slightly lower affinity, to histamine H1-receptors and α2-adrenoreceptors. It has no affinity for cholinoreceptors. Although risperidone is a potent D2 antagonist (which is thought to be the primary mechanism of improving the productive symptomatology of schizophrenia), it causes less pronounced suppression of motor activity and is less likely to induce catalepsy than classical neuroleptics. Because of its balanced antagonism to serotonin and dopamine receptors in the CNS, it reduces the likelihood of developing extrapyramidal side effects.


Risperdal (Risperidone) may induce a dose-dependent increase in plasma prolactin concentration.


Pharmacokinetics

After oral administration, risperidone is completely absorbed from the gastrointestinal tract, Cmax in plasma is reached within 1-2 hours. Food has no effect on the absorption of risperidone.


Css of risperidone in the body in most patients is reached within 1 day. Css of 9-hydroxyrisperidone is reached within 4-5 days. Plasma concentrations of risperidone are proportional to the dose (within the therapeutic dose range).


Risperdal (Risperidone) is rapidly distributed in the body, Vd is 1-2 l/kg. In plasma, risperidone binds to albumin and alpha1-glycoprotein. The binding of risperidone to plasma proteins is 88%, 9-hydroxyrisperidone - by 77%.


Risperdal (Risperidone) is metabolized in the liver with the participation of CYP2D6 isoenzyme to form 9-hydroxysperidone, which has pharmacological effects similar to those of risperidone. The antipsychotic effect is due to the pharmacological activity of risperidone and 9-hydroxysperidone. Another route of metabolism of risperidone is N-dealkylation.


After oral administration in patients with psychosis, the T1/2 of risperidone from plasma is 3 hours. The T1/2 of 9-hydroxysperidone and the active antipsychotic fraction is 24 hours.


After 1 week of use 70% is excreted in the urine, 14% - in the feces. The total content of risperidone and 9-hydroxyrisperidone in the urine is 35-45%. The remaining amount is due to inactive metabolites.


Elderly patients and patients with renal insufficiency showed increased plasma concentrations and delayed excretion of risperidone after a single oral administration.



Contraindications to use

Hypersensitivity to risperidone.

Administration during pregnancy and lactation

It is possible to use during pregnancy in case when the expected benefits of the therapy for a mother outweigh the potential risk for a fetus. If it is necessary to use during lactation, breast-feeding should be discontinued.

Administration in liver dysfunction

In schizophrenia with concomitant liver disease, an initial dose of 500 mcg 2 times daily is recommended. If necessary, the dose may be increased to 1-2 mg 2 times a day.

Administration in patients with renal dysfunction

In schizophrenia with concomitant renal disease, an initial dose of 500 mcg 2 times daily is recommended. If necessary, the dose may be increased to 1 to 2 mg twice a day.

Administration in children

No data on the safety of risperidone administration in children under 15 years of age are available.

Administration in elderly patients

In elderly patients with schizophrenia, a starting dose of 500 mcg 2 times per day is recommended. If necessary, the dose may be increased to 1-2 mg 2 times per day.

Indications of active substances of the drug Risperdal (Risperidone)

Treatment of schizophrenia (incl. First-time acute psychosis, acute onset schizophrenia, chronic schizophrenia); psychotic states with expressed productive (hallucinations, delusions, thought disorders, hostility, suspiciousness) and/or negative (blunted affect, emotional and social withdrawal, poor speech) symptomatology; for reduction of affective symptoms (depression, guilt, anxiety) in patients with schizophrenia; prevention of relapses (acute psychotic states) in chronic schizophrenia; treatment of behavioral disorders in patients with dementia with symptoms of aggressiveness (angry outbursts, physical violence), mental disorders (agitation, delirium) or psychotic symptoms; treatment of mania in bipolar disorders (as mood stabilizer as adjuvant therapy).

Dosing regimen

The optimal dosing regimen is determined by the doctor. Should be strictly in accordance with the drug used dosage form of a particular drug indications for use and dosing regimen.

Individual. When administered orally, the initial dose for adults is 0.25-2 mg/day, on day 2 - 4 mg/day. Thereafter, the dose may either be maintained at the same level or, if necessary, adjusted. Usually the optimal therapeutic dose, depending on indications, is in the range of 0.5-6 mg/day. In some cases, a slower dose increase and lower starting and maintenance doses may be warranted.


In schizophrenic patients of advanced age and with concomitant liver and kidney disease, an initial dose of 500 mcg 2 times/day is recommended. If necessary, the dose may be increased to 1-2 mg 2 times/day.


Maximum dose: in using risperidone in dose more than 10 mg/day there is no increase in efficacy compared to lower doses, but the risk of extrapyramidal symptoms increases. The safety of using risperidone in doses greater than 16 mg/day has not been studied, so further exceeding the dose is not allowed.