Requip

Availability: In Stock
Average Delivery Time: 9 Days
Exp. Date: April 2024
Package | Price | Per pill | Save | Order |
---|---|---|---|---|
Requip 2 mg | ||||
360 pills - 2 mg
+ 12 free Viagra 100 mg, 7% discount for future orders ![]() |
$575.99 | $1.60 | $743.89 | Add to cart |
270 pills - 2 mg
+ 12 free Viagra 100 mg, 7% discount for future orders ![]() |
$465.35 | $1.72 | $524.56 | Add to cart |
180 pills - 2 mg
+ 12 free Viagra 100 mg, 7% discount for future orders ![]() |
$324.99 | $1.81 | $334.95 | Add to cart |
120 pills - 2 mg
+ 8 free Viagra 100 mg, 5% discount for future orders ![]() |
$246.96 | $2.06 | $193.00 | Add to cart |
90 pills - 2 mg
+ 8 free Viagra 100 mg, 5% discount for future orders ![]() |
$205.97 | $2.29 | $124.00 | Add to cart |
60 pills - 2 mg
+ 4 free Viagra 100 mg, 3% discount for future orders |
$163.93 | $2.73 | $56.05 | Add to cart |
30 pills - 2 mg
+ 4 free Viagra 100 mg, 3% discount for future orders |
$109.99 | $3.67 | No | Add to cart |
Requip 1 mg | ||||
360 pills - 1 mg
+ 12 free Viagra 100 mg, 7% discount for future orders ![]() |
$459.99 | $1.28 | $379.89 | Add to cart |
270 pills - 1 mg
+ 12 free Viagra 100 mg, 7% discount for future orders ![]() |
$359.99 | $1.33 | $269.92 | Add to cart |
180 pills - 1 mg
+ 8 free Viagra 100 mg, 5% discount for future orders ![]() |
$251.99 | $1.40 | $167.95 | Add to cart |
120 pills - 1 mg
+ 4 free Viagra 100 mg, 3% discount for future orders |
$185.93 | $1.55 | $94.03 | Add to cart |
90 pills - 1 mg
+ 4 free Viagra 100 mg, 3% discount for future orders |
$154.94 | $1.72 | $55.03 | Add to cart |
60 pills - 1 mg
+ 4 free Viagra 100 mg, 3% discount for future orders |
$111.95 | $1.87 | $28.03 | Add to cart |
30 pills - 1 mg | $69.99 | $2.33 | No | Add to cart |
Requip 0.25 mg | ||||
360 pills - 0.25 mg
+ 4 free Viagra 100 mg, 3% discount for future orders |
$181.93 | $0.51 | $177.95 | Add to cart |
180 pills - 0.25 mg | $95.91 | $0.53 | $84.03 | Add to cart |
120 pills - 0.25 mg | $73.97 | $0.62 | $45.99 | Add to cart |
90 pills - 0.25 mg | $62.93 | $0.70 | $27.04 | Add to cart |
60 pills - 0.25 mg | $49.95 | $0.83 | $10.03 | Add to cart |
30 pills - 0.25 mg | $29.99 | $1.00 | No | Add to cart |
Requip 0.5 mg | ||||
360 pills - 0.5 mg
+ 8 free Viagra 100 mg, 5% discount for future orders ![]() |
$285.99 | $0.79 | $193.89 | Add to cart |
270 pills - 0.5 mg
+ 8 free Viagra 100 mg, 5% discount for future orders ![]() |
$221.95 | $0.82 | $137.96 | Add to cart |
180 pills - 0.5 mg
+ 4 free Viagra 100 mg, 3% discount for future orders |
$155.27 | $0.86 | $84.67 | Add to cart |
120 pills - 0.5 mg
+ 4 free Viagra 100 mg, 3% discount for future orders |
$109.99 | $0.92 | $49.97 | Add to cart |
90 pills - 0.5 mg | $88.97 | $0.99 | $31.00 | Add to cart |
60 pills - 0.5 mg | $65.95 | $1.10 | $14.03 | Add to cart |
30 pills - 0.5 mg | $39.99 | $1.33 | No | Add to cart |
Product description
DRUG TITLE
Requip (Ropinirole)
Pharmacological action
Antiparkinsonian drug, dopamine receptor agonist of non-ergoline structure. Its structure is similar to dopamine and it binds especially actively to D2- and D3-subtype receptors, acting also on presynaptic autoreceptors. In the early stage of Parkinson's disease, ropinirole is as effective as levodopa and more effective than bromocriptine. During the 3-year study ropinirole provided adequate correction of antiparkinsonian symptoms in 60% of patients. In late-stage Parkinson's disease, ropinirole in combination with levodopa reduced the duration of the off period by 12% and allowed a 31% reduction in the levodopa dose.
Pharmacokinetics
After oral administration, it is rapidly absorbed from the gastrointestinal tract. Cmax in plasma is reached after 1-2 hours. Bioavailability is about 85%. Binding to plasma proteins is about 40%. Metabolized in the liver to form inactive metabolites. Vd - 7.5 l/kg.
Contraindications for use
Severe renal insufficiency, severe hepatic insufficiency, pregnancy, lactation (breast-feeding), hypersensitivity to ropinirole.
Administration during pregnancy and lactation
It is contraindicated for use during pregnancy and lactation (breast-feeding).
Administration in patients with liver dysfunction
Acute hepatic insufficiency is contraindicated.
Administration in patients with kidney dysfunction
Contraindicated in severe hepatic insufficiency.
Administration in children
It is not recommended to use in children and teenagers below 18 years of age.
Indications of the active substance ROPINIROL
Parkinson's disease.
Dosage regimen
It is taken orally. During 1 week - 25 mcg 3 times/day, during 2 weeks - 500 mcg 3 times/day, during 3 weeks - 750 mcg 3 times/day, during 4 weeks - 1 mg 3 times/day. Later the dose may be increased by 0.5-1 mg three times a day (1.5-3 mg/day). Therapeutic effect is usually achieved at doses of 3-9 mg/day. If symptoms persist, the dose may be increased to 24 mg/day.