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Lasix

Lasix
Lasix is ​​prescribed for edema syndrome of various origins, liver cirrhosis, nephrotic syndrome, pulmonary edema, cardiac asthma, cerebral edema, eclampsia, forced diuresis, severe hypertension, some forms of hypertensive crisis, hypercalcemia.

Brand: Furosemide

Availability: In Stock
Average Delivery Time: 9 Days
Exp. Date: December 2023
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Package Price Per pill Save Order
Lasix 100 mg
360 pills - 100 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$147.95 $0.41 $211.93 Add to cart
270 pills - 100 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$116.28 $0.43 $153.63 Add to cart
180 pills - 100 mg $85.93 $0.48 $94.01 Add to cart
120 pills - 100 mg $65.25 $0.54 $54.71 Add to cart
90 pills - 100 mg $54.97 $0.61 $35.00 Add to cart
60 pills - 100 mg $45.95 $0.77 $14.03 Add to cart
30 pills - 100 mg $29.99 $1.00 No Add to cart
Lasix 40 mg
360 pills - 40 mg $91.99 $0.26 $123.71 Add to cart
270 pills - 40 mg $75.96 $0.28 $85.82 Add to cart
180 pills - 40 mg $59.75 $0.33 $48.10 Add to cart
120 pills - 40 mg $45.98 $0.38 $25.92 Add to cart
90 pills - 40 mg $43.93 $0.49 $10.00 Add to cart
60 pills - 40 mg $35.95 $0.60 No Add to cart

Product description

Pharmacokinetics of the drug Lasix

Buy Lasix in Canada

When taken orally, bioavailability is 64%. Cmax increases with increasing dose, but the time to reach the maximum does not depend on the dose and varies widely depending on the patient's condition. T1/2 - about 2 hours In plasma, 91–99% binds to protein, 2.4–4.1% is in a free state. Biotransformed mainly into glucuronide. It is excreted in the urine (after intravenous administration more than when taken orally).

Clinical pharmacology

The onset of the diuretic effect when ingested is observed already within 1 hour, the maximum action - after 1–2 hours, duration - 6–8 hours. With intravenous administration, the onset of action - after 5 minutes, maximum - after 30 minutes, duration - about 2 hours. When administered intravenously, it causes varicose veins, rapidly reduces preload, reduces pressure in the left ventricle and the pulmonary artery system, and reduces systemic pressure.

Indications for Lasix®

Lasix in the treatment of pulmonary edema

Edema syndrome of various origins (cardiac, hepatic, renal after the second month of pregnancy, intoxication), pulmonary and cerebral edema, arterial hypertension, forced diuresis, renal failure.

Dosing and Administration of the drug Lasix

Lasix drug appearance

Inside, usually prescribed on an empty stomach; IV is administered for at least 1–2 minutes. In mild edematous syndrome, the initial dose for adults is 20–80 mg when taken orally or 20–40 mg IV; in the case of persistent edema - the same or increasing by 20–40 mg (by 20 mg for parenteral administration), the dose can be re-administered no earlier than 6–8 hours (2 hours for parenteral administration) until a diuretic effect is obtained; such an individually adjusted dosage can be applied 1 or 2 times a day. The greatest efficiency is achieved when the drug is taken 2-4 days a week. For children, the initial dosage is 2 mg / kg of body weight (for parenteral administration - 1 mg / kg), if the effect is unsatisfactory, it can be increased by 1-2 mg / kg (for parenteral administration - by 1 mg / kg), but not earlier than after 6-8 hours (for parenteral administration, this period is at least 2 hours). With arterial hypertension, the initial dosage for adults is 80 mg per day in 2 divided doses. In case of pulmonary edema, Lasix is ​​administered intravenously at a dose of 40 mg, if necessary, after 20 minutes, the drug can be administered at a dose of 20 to 40 mg.

Contraindications

Hypersensitivity (including to other sulfone and sulfonamides), acute glomerulonephritis, renal failure with anuria, hepatic coma, impaired water-salt balance and acid base balance (hypokalemia, hyponatremia).

Application during pregnancy and lactation

During pregnancy, it should be used according to strict indications and only for a short time. During treatment, breastfeeding should be suspended.

Precautions

You should take into account a possible decrease in the reaction rate (prescribe carefully when driving and servicing mechanisms).

Side effects

Hypotension, arrhythmia, dry mouth, nausea, vomiting, diarrhea, pancreatitis, hypovolemia, dehydration, hypokalemia, hyponatremia, hypochloremia, metabolic alkalosis, hypocalcemia, hyperuricemia, dermatitis, hearing impairment, dizziness, paresthesia, muscular retention urine in patients with prostate adenoma, hypercholesterolemia, hypertriglyceridemia, decreased glucose tolerance, acute pancreatitis, allergic reactions (rash, fever, vasculitis, interstitial nephritis); in premature babies - nephrocalcinosis.