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Imdur

Imdur
Imdur (isosorbide mononitrate) is a nitrate that dilates (dilates) blood vessels, making it easier for blood to pass through them and making it easier for the heart to pump.

Brand: Isosorbide

Availability: In Stock
Average Delivery Time: 9 Days
Exp. Date: April 2024
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Package Price Per pill Save Order
Imdur 60 mg
180 pills - 60 mg
+ 8 free Viagra 100 mg, 5% discount for future orders
$215.09 $1.19 $97.81 Add to cart
120 pills - 60 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$155.61 $1.30 $52.99 Add to cart
90 pills - 60 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$125.05 $1.39 $31.40 Add to cart
60 pills - 60 mg $89.93 $1.50 $14.37 Add to cart
30 pills - 60 mg $52.15 $1.74 No Add to cart
Imdur 40 mg
240 pills - 40 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$195.95 $0.82 $171.97 Add to cart
120 pills - 40 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$107.92 $0.90 $76.04 Add to cart
90 pills - 40 mg $93.91 $1.04 $44.06 Add to cart
60 pills - 40 mg $71.95 $1.20 $20.03 Add to cart
30 pills - 40 mg $45.99 $1.53 No Add to cart
Imdur 30 mg
360 pills - 30 mg
+ 8 free Viagra 100 mg, 5% discount for future orders
$281.95 $0.78 $245.93 Add to cart
180 pills - 30 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$149.99 $0.83 $113.95 Add to cart
120 pills - 30 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$101.93 $0.85 $74.03 Add to cart
90 pills - 30 mg $87.94 $0.98 $44.03 Add to cart
60 pills - 30 mg $66.97 $1.12 $21.01 Add to cart
30 pills - 30 mg $43.99 $1.47 No Add to cart
Imdur 20 mg
360 pills - 20 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$195.91 $0.54 $186.89 Add to cart
180 pills - 20 mg
+ 4 free Viagra 100 mg, 3% discount for future orders
$111.95 $0.62 $79.45 Add to cart
120 pills - 20 mg $81.93 $0.68 $45.67 Add to cart
90 pills - 20 mg $67.95 $0.76 $27.75 Add to cart
60 pills - 20 mg $51.92 $0.87 $11.88 Add to cart
30 pills - 20 mg $31.90 $1.06 No Add to cart

Product description

Pharmacokinetics of the drug Imdur

Buy Imdur in Canada

Quickly and completely absorbed after oral administration, bioavailability - from 90 to 100%. The time to reach the therapeutic concentration is 30 minutes and is 100 ng / ml. Cmax in blood plasma - 8 hours. Plasma protein binding is less than 4%. Isosorbide mononitrate is almost completely metabolized in the liver. The metabolites are pharmacologically inactive. It is excreted by the kidneys almost exclusively in the form of metabolites. Approximately 2% is displayed unchanged. T1/2 - 4–5 h.

What is Imdur?

Imdur (isosorbide mononitrate) is a nitrate that dilates (dilates) blood vessels, making it easier for blood to pass through them and making it easier for the heart to pump.

Imdur is an extended-release tablet used to prevent attacks of angina pectoris (chest pain).

Imdur will not treat an angina attack that has already begun.

Important information

Imdur for the treatment of heart problems

You should not take medications for erectile dysfunction (Viagra, Cialis, Levitra, Stendra, Staxin, Sildenafil, Avanafil, Tadalafil, Vardenafil) while you are taking Imdur. Taking these medicines together can cause a sudden and severe drop in blood pressure.

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Seek emergency medical attention if you have early symptoms of a heart attack (chest pain or pressure, pain spreading to the jaw or shoulder, sweating, general ill feeling).

Do not suddenly stop taking this medicine. Stopping suddenly can cause a severe attack of angina.

Isosorbide mononitrate can cause severe headaches, especially when you start using it. These headaches may gradually become less severe as you continue to use the medication. Do not stop taking Imdur. Ask your doctor before using any pain relievers.

Use this medication regularly to help prevent angina attacks. Get your prescription filled before you run out of medication completely.

Imdur Dosing Information

Angina Pectoris

Usual Adult Dose for Prevention:

EXTENDED RELEASE:

30-60 mg orally once a day in the morning

Maximum dose: 240 mg orally once a day in the morning

Comments:

-Turn everything (do not crush or chew) with half glass liquid.

-Start at the bottom of the dosage range for elderly patients.

Application: Prevention of angina pectoris due to coronary artery disease; The onset of action is not fast enough to be useful in interrupting an acute anginal episode.

Usual Adult Dose for Angina Pectoris:

EXTENDED RELEASE:

30-60 mg orally once a day in the morning

Maximum dose: 240 mg orally once a day in the morning

Overdose

Symptoms: marked decrease in blood pressure with orthostatic dysregulation, palpitations, weakness, dizziness, lethargy, headache, skin redness, nausea, vomiting, diarrhea, collapse, fainting, hyperthermia, convulsions, sweating, methemoglobinemia, dyspnoeaemia, anoxnoemia , increased intracranial pressure, paralysis, coma.

Treatment: gastric lavage; with a pronounced decrease in blood pressure and / or a state of shock, fluid should be administered; in exceptional cases, norepinephrine and / or dopamine infusions can be used to improve blood circulation. Administration of epinephrine (adrenaline) and related compounds is contraindicated.

Depending on the severity, in cases of methemoglobinemia, the following antidotes are used:

1) vitamin C: 1 g orally or in the form of sodium salt i / v;

2) methylene blue: up to 50 ml of 1% solution of methylene blue i / v;

3) toluidine blue: first, 2–4 mg / kg of body weight, strictly iv; then, if necessary, repeated injections of 2 mg / kg of body weight are possible with an interval between injections of 1 hour;

4) oxygen therapy, hemodialysis, exchange blood transfusion.

What other drugs will affect Imdur?

Taking Imdur with certain other medicines can result in significantly low blood pressure. This includes medicine to treat erectile dysfunction or pulmonary arterial hypertension. Serious, life-threatening side effects can occur.

Tell your doctor about all of your current medicines and what you start or stop using, especially:

  • Avanafil (Stendra);

  • A diuretic or "water pill";

  • nitroglycerine;

  • Riociguat (Adempas);

  • Sildenafil (Viagra, Revatio);

  • Tadalafil (Cialis, Adtsirka); or

  • Vardenafil (Levitra, Staksin).

Side effects

Headache, dizziness, tinnitus, facial flushing, tachycardia, hypotension, nausea, vomiting, gastralgia, methemoglobinemia, allergic reactions.

Tachycardia, orthostatic hypotension, fainting, collapse, involuntary urination, headache, dizziness, anxiety, dyspeptic symptoms, skin redness.