Cytoxan
Brand: Cyclophosphamide
Availability: In Stock
Average Delivery Time: 9 Days
Exp. Date: April 2024
| Package | Price | Per pill | Save | Order |
|---|---|---|---|---|
| Cytoxan 50 mg | ||||
|
180 pills - 50 mg
+ 8 free Viagra 100 mg, 5% discount for future orders  |
$229.03 | $1.27 | $83.33 | Add to cart |
|
120 pills - 50 mg
+ 4 free Viagra 100 mg, 3% discount for future orders |
$155.01 | $1.29 | $53.23 | Add to cart |
|
90 pills - 50 mg
+ 4 free Viagra 100 mg, 3% discount for future orders |
$117.99 | $1.31 | $38.19 | Add to cart |
| 60 pills - 50 mg | $85.54 | $1.43 | $18.58 | Add to cart |
| 30 pills - 50 mg | $52.06 | $1.74 | No | Add to cart |
Product description
Pharmacological action of Cytoxan
Pharmacological action - immunosuppressive, cytostatic, antitumor.
It binds to the nucleophilic regions of macromolecules, inhibits mitosis and cell metabolism (primarily, with uncontrolled growth).
Pharmacokinetics
It is activated in the liver with the participation of cytochrome P450 with the formation of metabolites with an alkylating effect.
Indications of the drug Cytoxan
Malignant lymphomas (lymphocytic and histiocytic lymphoma, lymphogranulomatosis, Burkitt's lymphoma, mixed type lymphoma), multiple myeloma, leukemia (lymphocytic leukemia, granulocytic leukemia, myeloid leukemia, acute lymphoblastic leukemia in children), mycosis, fungal retinitis breast carcinoma.
Route of administration and dose
IV, 40-50 mg / kg in several doses for 2-5 days or 10-15 mg / kg with an interval of 7-10 days, or 3-5 mg / kg 2 times a a week (before use, the contents of the bottle are dissolved in 5–100 ml of water for injection or other solvent to a concentration of 20 mg / ml).
Contraindications
Hypersensitivity, severe myelosuppression.
Application during pregnancy and lactation
During pregnancy and lactation, it can be used only for health reasons.
Precautions
Precautions are prescribed to patients with myelosuppression, impaired liver and kidney function, with previous radiation and chemotherapy. During treatment, it is necessary to regularly monitor the cellular composition of blood and urine (for the presence of red blood cells). For women of childbearing age, reliable contraception is recommended.
Side effects
Reproductive disorders, nausea, vomiting and other dyspeptic phenomena, ulcerative stomatitis, myelosuppression, cystitis, urethritis, renal and cardiac dysfunction, induction of secondary infections and malignant tumors, fibrosis (lungs, bladder), alopecia, skin rashes, pigmentation skin changes, nail changes, anaphylactoid reactions.