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Cytoxan is an alkylating antineoplastic agent that also has an immunosuppressive effect. It is an inactive transport form that breaks down under the action of phosphatases with the formation of an active component directly in tumor cells, "attacks" the nucleophilic centers of protein molecules, disrupts the synthesis of DNA and RNA, and blocks mitotic division.

Brand: Cyclophosphamide

Availability: In Stock
Average Delivery Time: 9 Days
Exp. Date: June 2024
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Cytoxan 50 mg
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Product description

Pharmacological action of Cytoxan 

Buy Cytoxan in Canada

Pharmacological action - immunosuppressive, cytostatic, antitumor.

It binds to the nucleophilic regions of macromolecules, inhibits mitosis and cell metabolism (primarily, with uncontrolled growth).


It is activated in the liver with the participation of cytochrome P450 with the formation of metabolites with an alkylating effect.

Indications of the drug Cytoxan

Treating cancerous tumors with Cytoxan

Malignant lymphomas (lymphocytic and histiocytic lymphoma, lymphogranulomatosis, Burkitt's lymphoma, mixed type lymphoma), multiple myeloma, leukemia (lymphocytic leukemia, granulocytic leukemia, myeloid leukemia, acute lymphoblastic leukemia in children), mycosis, fungal retinitis breast carcinoma.

Route of administration and dose

Appearance of tablets Cytoxan

IV, 40-50 mg / kg in several doses for 2-5 days or 10-15 mg / kg with an interval of 7-10 days, or 3-5 mg / kg 2 times a a week (before use, the contents of the bottle are dissolved in 5–100 ml of water for injection or other solvent to a concentration of 20 mg / ml).


Hypersensitivity, severe myelosuppression.

Application during pregnancy and lactation

During pregnancy and lactation, it can be used only for health reasons.


Precautions are prescribed to patients with myelosuppression, impaired liver and kidney function, with previous radiation and chemotherapy. During treatment, it is necessary to regularly monitor the cellular composition of blood and urine (for the presence of red blood cells). For women of childbearing age, reliable contraception is recommended.

Side effects

Reproductive disorders, nausea, vomiting and other dyspeptic phenomena, ulcerative stomatitis, myelosuppression, cystitis, urethritis, renal and cardiac dysfunction, induction of secondary infections and malignant tumors, fibrosis (lungs, bladder), alopecia, skin rashes, pigmentation skin changes, nail changes, anaphylactoid reactions.