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|Artane 2 mg|
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|90 pills - 2 mg||$43.25||$0.48||$12.24||Add to cart|
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Antiparkinsonian drug. It has a strong central n-cholinoblocking action as well as peripheral m-cholinoblocking action. The central action reduces or eliminates motor disorders associated with extrapyramidal disorders.
In parkinsonism, it reduces tremor, and to a lesser extent affects rigidity and bradykinesia.
It has an antispasmodic effect that is associated with anticholinergic activity and direct myotropic action.
After oral administration, it is rapidly absorbed from the gastrointestinal tract.
T1/2 is on average 6-10 hours. Artane (Trihexyphenidyl) is excreted mainly unchanged. It does not cumulate.
It penetrates easily through the HEB.
Contraindications to use
Hypersensitivity to Artane (Trihexyphenidyl); mechanical stenosis of the gastrointestinal tract, megacolon, closed-angle glaucoma, urinary retention, prostatic hyperplasia (with residual urine), tachyarrhythmias, acute alcohol poisoning, psychotropic medications, including opioids. including opioids, tardive dyskinesia (because trihexyphenidyl may provoke or aggravate tardive dyskinesia); pregnancy, breastfeeding; children and adolescents under 18 years of age.
Tachycardia, arterial hypertension, prostatic hyperplasia, psychotic and manic disorders, dementia syndrome, acute myocardial infarction, myasthenia gravis, glaucoma, elderly patients, patients with heart disease, uncompensated kidney or liver disease, obstructive GI or urinary and genital tract disease.
Administration during pregnancy and lactation
It is contraindicated for use during pregnancy and lactation (breast-feeding). If it is necessary to use during lactation, it is necessary to decide whether or not to stop breastfeeding.
Indications of active ingredients of the drug Artane (Trihexyphenidyl)
Parkinsonism; prevention and control of drug-induced extrapyramidal symptoms (except tardive dyskinesia).
Orally. The dose, regimen and duration of therapy are determined individually, depending on the indications, clinical situation, and effectiveness of therapy.
The optimal dosing regimen is determined by the physician. The dosage form used for a particular drug should be strictly observed in accordance with the indications for use and the dosing regimen.